INHIBIT CLASIFICATION ANTIBIOTICS Beta-Lactamase inhib Clavulanic Acid Penicinillase - Sensible Ampicillin Amoxicillin Aminopenicillins rum Natural Penicillins Penicillin G Na K Procainic Benzathine IV IM Penicinillase - Resistant very narrow spectrum Antipseudomonal extended spectrum Penicillins narrow spectrum Penicillin VK VO Oxacillin Dicloxacillin Carboxipenicillins Ureidopenicillins 1° Generation carcillin Carbenicillin Piperacillin Cephalexine Cephradrine Cefuroxime Cefadroxil Cefprozil Cefotetan 2° Generation Cefoperazone Ceftriaxone Cefpodoxime Ceftizoxime Ceftibuten Loracarbef Cefixime Cefotaxime Ceftazidime Cephalosporins 3° Generation Cefditoren Cefpirome* Ceftolozane 4° Generation Cefepime 5° Generation Carbapenems Monobactams Glycopeptides Meropenem Ertapenem DoripenemImipenem Cylastatine Aztreonam Telavancin Dalbavancin Oritavancin Isoniazid Vancomycin Daptomycin Gentamicin Neomycin Minocycline Demeclocylin* Tobramycin Amino glycosides Tetracyclins Streptomycin Doxycycline Tetracyclin Tigecyclirn Linezolid Oxazolidonones Streptogramins QuinupristinDalfopristin Cloramphenicol Macrolides Lincosamides 50S Erythromycin Azithromycin Clarithromycin Clindamycin Lincomycin DNA topoisomerases Moxifloxacin Ofloxacin Levofloxacin Enofloxacin Fluorquinolones Ciprofloxacin Norfloxacin Gemifloxacin Sparfloxacin Quinolones Nalidixic Acid Sulfonamides Sulfamethoxazole Ag Sulfadiazine Sulfasalazine Sulfisoxazole Trimethoprim TMP Metronidazole DHFR inhibitors Pyrimethamine DNA damage mRNA synthRifampim Nitroimidazoles <p><a href=httpmynotes4usmletumblrcompost94603349785antibiotics-cheat-sheet-also-remember class=tumblr_blog>mynotes4usmle<a><p> <blockquote><p><b>ANTIBIOTICS CHEAT SHEET <b><p> <p>Also REMEMBER!!!!<p> <p><b>* Sulfonamides<b> compete for albumin with<p> <ul><li><b>Bilirrubin <b>given in 2°3°T high risk or indirect hyperBb and kernicterus in premies<li> <li><b>Warfarin <b>increases toxicity bleeding<li> <ul><p>* <b>Beta-lactamase penicinillase Suceptible<b><p> <ul><li>Natural Penicillins G V F K<li> <li>Aminopenicillins Amoxicillin Ampicillin<li> <li>Antipseudomonal Penicillins Ticarcillin Piperacillin<li> <ul><p>* <b>Beta-lactamase penicinillase Resistant<b><p> <ul><li>Oxacillin Nafcillin Dicloxacillin<li> <li>3°G 4°G Cephalosporins<li> <li>Carbapenems <li> <li>Monobactams<li> <li>Beta-lactamase inhibitors<li> <ul><p><b>* Penicillins<b> enhanced with<p> <ul><li><b>Clavulanic acid &amp Sulbactam<b> both are suicide inhibitors they inhibit beta-lactamase<li> <li><b>Aminoglycosides<b> against enterococcus and psedomonas<li> <ul><p>* <b>Aminoglycosides <b>enhanced with <b>Aztreonam<b><p> <p><b>*<b> Penicillins renal clearance EXCEPT <b>Oxacillin &amp Nafcillin <b>bile<p> <p><b>*<b> Cephalosporines renal clearance EXCEPT <b>Cefoperazone &amp Cefrtriaxone <b>bile<p> <p>* Both inhibited by <b>Probenecid<b> during tubular secretion<p> <p><b>* 2°G Cephalosporines <b>none cross BBB except <b>Cefuroxime<b><p> <p><b>* 3°G Cephalosporines <b>all cross BBB except <b>Cefoperazone<b> bc is highly highly lipid soluble so is protein bound in plasma therefore it doesn’t cross BBB<p> <p><b>* Cephalosporines <b>are &quot<b>LAME<b>“ bc they do <b>not cover<b> this organisms <p> <ul><li><b>L <b>isteria monocytogenes<li> <li><b>A <b>typicals Mycoplasma Chlamydia<li> <li><b>M <b>RSA <b>except Ceftaroline 5°G<b><li> <li><b>E <b> nterococci<li> <ul><figure class=tmblr-full data-orig-height=282 data-orig-width=500 data-orig-src=https78mediatumblrcomfefa0e57bd8663f41e32258e9f58f135tumblr_inline_mvv7hx19421r9he9mgif><img src=https78mediatumblrcomcdf6c898d35c4d91aa1f3e6bd9a98462tumblr_inline_p7g6owpmSr1scxgwx_540gif alt=image data-orig-height=282 data-orig-width=500 data-orig-src=https78mediatumblrcomfefa0e57bd8663f41e32258e9f58f135tumblr_inline_mvv7hx19421r9he9mgif><figure><p>* Disulfiram-like effect <b>Cefotetan <b>&amp <b>Cefoperazone <b><i><b><a href=httpmynotes4usmletumblrcompost72610336163drugs-that-cause-disulfiram-like-effects-mnemonic#U98PPPl5Mms>mnemonic<a><b><i><b><br><b><p> <p><b>* Cefoperanzone <b>all the exceptions!!!<p> <ul><li>All 3°G cephalosporins cross the BBB except Cefoperazone<li> <li>All cephalosporins are renal cleared except Cefoperazone<li> <li>Disulfiram-like effect<li> <ul><p>* Against <b><i>Pseudomonas<i><b><p> <ul><li>3°G <b>Cef taz idime <b>taz taz taz taz<li> <li>4°G <b>Cefepime Cefpirome <b>not available in the USA<li> <li><b>Antipseudomonal penicillins<b><li> <li><b>Aminoglycosides <b>synergy with beta-lactams<li> <li><b>Aztreonam <b>pseudomonal sepsis<li> <ul><p>* Covers <b>MRSA <b><b>Ceftaroline <b>rhymes w Caroline Caroline the 5°G Ceph <b>Vancomycin <b><b>Daptomycin <b><b>Linezolid <b><b>Tigecycline<b><p> <p><b>* <b>Covers <b>VRSA Linezolid DalfopristinQuinupristin<b><p> <p><b>* Aminoglycosides<b> decrease release of ACh in synapse and act as a Neuromuscular blocker this is why it enhances effects of muscle relaxants<p> <p><b>* DEMECLOCYCLINE <b>tetracycline that’s not used as an AB it is used as tx of SIADH to cause Nephrogenic Diabetes Insipidus inhibits the V2 receptor in collecting ducts<p> <p>* Phototoxicity <b>Q<b> ue<b> S T <b> ion?<p> <ul><li><b>Q <b>uinolones<li> <li><b>S<b>ulfonamides<li> <li><b>T<b> etracyclines<li> <ul><figure class=tmblr-full data-orig-height=281 data-orig-width=500 data-orig-src=https78mediatumblrcom7af835b2dc618c0aac3a1186d5ee68fbtumblr_inline_n9rlcbPQ271r9he9mgif><img src=https78mediatumblrcom7af835b2dc618c0aac3a1186d5ee68fbtumblr_inline_p7g6owDZDE1scxgwx_540gif alt=image data-orig-height=281 data-orig-width=500 data-orig-src=https78mediatumblrcom7af835b2dc618c0aac3a1186d5ee68fbtumblr_inline_n9rlcbPQ271r9he9mgif><figure><p>* <b><a href=httpmynotes4usmletumblrcompost62061356766cyp450-inducers-inhibitors-mnemonic#U-RmDfl5Mms>p450 inhibitors<a><b> Cloramphenicol Macrolides except Azithromycin Sulfonamides<p> <p>* <b>Macrolides SE Motilin<b> stimulation <b>QT prolongation<b> reversible <b>deafness<b> <b>eosinophilia<b> <b>cholestatic<b> hepatitis<p> <p>* <b>Bactericidal <b>beta-lactams penicillins cephalosporins monobactams carbapenems aminoglycosides fluorquinolones metronidazole<p> <p><b>* Baceriostatic <b>tetracyclins streptogramins chloramphenicol lincosamides oxazolidonones macrolides sulfonamides DHFR inhibitors<p> <p>* <b>Pseudomembranous colitis <b>Ampicillin Amoxicillin Clindamycin Lincomycin<p> <p>* <b>QT prolongation <b>macrolides sometimes fluoroquinolones<p><blockquote> Meme

bbb

Bilbo

Drugs

gif

Protein

tumblr

Blog

Covers

Cross

Diabetes

found @ 34 likes ON 2018-05-22 22:44:55 BY astrologymemes.com

source: tumblr